How to implement a lock in JavaScript

How could something equivalent to lock in C# be implemented in JavaScript?

So, to explain what I'm thinking a simple use case is:

User clicks button B. B raises an onclick event. If B is in event-state the event waits for B to be in ready-state before propagating. If B is in ready-state, B is locked and is set to event-state, then the event propagates. When the event's propagation is complete, B is set to ready-state.

I could see how something close to this could be done, simply by adding and removing the class ready-state from the button. However, the problem is that a user can click a button twice in a row faster than the variable can be set, so this attempt at a lock will fail in some circumstances.

Does anyone know how to implement a lock that will not fail in JavaScript?