Interactive plotting in Python?

Matlab and Mathematica both have features that allow the user to manipulate the contents of a plot using, say, a slider. For example, if you have a set of 3D data, it is easy to make a small program that lets you view 2D slices of a set of 3D data where the user can slide a slider to move through which slice is displayed. Is there anything in python that allows for this sort of capability without tons of effort? For example, is it possible to do such a thing in matplotlib, or something similar? I

Thanks.