Dealing with Schema Updates in nHibernate/Fluent nHibernate after Deployment

In writing an application that runs on Fluent Nhibernate/Nhibernate, something has me a bit concerned. I suppose this would be true of any ORM (and even without using an ORM), but what is the ... I guess the word is 'field of study' that relates to the best practices and methods for updating a database after deployment?

In nHibernate, I establish a SessionFactory and have an initial run where it writes the database out based on the mappings. That's fine and good, I can even write the database out manually. But what about when my client comes back and wants something new added? Can I append to the database without losing my data? I am completely new to all of this and it has been troubling me since the start of this project, and I really do not know what direction to go to make sure I can manage the program after it is deployed.

I have looked at other stack overflow questions that I could find regarding this topic - one of which did not even have an accepted answer (though the question itself was kind of vague), but I did discover the tool http://www.red-gate.com/products/sql-development/sql-compare/ from the question Tool to upgrade SQL Express database after deployment though I am wondering just how good of a 'strategy' that is.