Web deploy and folder permissions

I'm using VS 2010 to build the deployment package for a web application. I manually deploy it to the IIS 6.0 server using the deployment ccommand script it generates. All the stuff gets copied under the Inetpub default website properly. The only issue I have is that the folder permissions keep getting reset once I deploy.

Say my website is under the folder "Mywebsite". I grant certain user XYS full control to this folder. All is well. The next time I deploy, user XYZ no longer has full control and the permissions gets reset.